Using Glucose to Treat Hypoglycemia – Diabetes Daily


This content originally appeared on Beyond Type 1. Republished with permission.

By Ginger Vieira

If you could relieve the symptoms of low blood sugar sooner and faster—would you?

We’re generally told to eat 15 grams of fast-acting carbohydrates when treating a low blood sugar—but one type of sugar is truly the fastest.

While being prepared for low blood sugar emergencies with fast-acting carbohydrates is the goal, we’ve all found ourselves low at times when we have to use less-than-ideal foods.

Here, we’ll discuss why treating low blood sugars with glucose (dextrose) is the fastest way to raise your blood sugar.

Glucose vs. Fructose vs. Sucrose

There are several very good reasons why glucose tabs are encouraged over a bowl of ice cream or even a handful of grapes when it comes to treating low blood sugar. While the fat and protein in that ice cream slow down the digestion of the sugar, the type of sugar in any carbohydrate source matters, too.

Here are the three main types of sugar found in food:

  • Glucose/Dextrose: Raises blood sugar levels immediately because it is already in the form of sugar your brain and cells recognize and require for fuel
  • Fructose: Does not actually breakdown into glucose and raises your blood sugar, because fructose must be metabolized by the liver
  • Sucrose: Known as a “double sugar” because it’s made of equal parts of glucose and fructose, which means only half of its contents can raise blood sugar

Let’s take a closer look at these three types of sugar and their impact on your next low blood sugar.

Glucose / Dextrose

Glucose—also known as dextrose—immediately raises blood sugar levels. Unlike sucrose or fructose, glucose is already in a form your body can use, making it the most rapidly-absorbed source of carbohydrate you can choose.

The faster you can raise your blood sugar, the sooner you can calm down the uncomfortable (and often scary) symptoms of low blood sugar.

  • Sources of 100% glucose include: Dex4 glucose tabs, glucose gel, Smarties, Pixie Stix

When you choose these sources of carbohydrate to treat a low, your blood sugar will likely rise significantly faster than choosing a piece of fruit, a juice box, a candy bar, or even a spoonful of honey.

That being said, there are some plant-based foods that contain more glucose than others—including grapes, cherries, honey, and corn syrup (not to be confused with high fructose corn syrup).

If you’ve ever wondered why a bowl full of raspberries has such a lower impact on your blood sugars than the same amount of carbohydrates from a bowl of grapes, it’s all about the amount of glucose vs. fructose vs sucrose.

For example, here’s the breakdown of different types of fruit.

*Look at the different sugar contents of more fruits in this table.


Fructose is found naturally in most plant-based foods, we think of these as naturally healthy sources of carbohydrates. Unfortunately, they actually aren’t ideal for treating low blood sugars.

  • Sources of fructose include: fruit, honey, agave, juice, pasta, bread, veggies, and many more processed foods

The problem is that fructose on its own does not actually break down into glucose to raise your blood sugar. Instead, fructose is first metabolized by the liver and can raise triglyceride levels and promote fatty liver when consumed in large amounts. Diets high in fructose are also associated with higher levels of belly fat. (This is specifically why “high fructose corn syrup” is a concerning ingredient in many processed foods.)

Of course, we all know an apple raises your blood sugar—this is because most foods that contain fructose also contain varying amounts of glucose and sucrose.

If you use an apple or even a juice box to treat low blood sugar, only a percentage of the carbohydrates in that apple are going to raise your blood sugar. Your body also has to break down the fibrous apple in order for the sucrose and glucose it contains to reach your bloodstream. This takes longer than using a glucose tab where the digestion process is nearly instant.

Choosing carbohydrates that contain a great deal of fructose for low blood sugars also means you’re consuming calories that are not helping you. Treating frequent low blood sugars with more calories than you need can make it more challenging to manage your personal weight goals and lead to gradual weight gain.


Sucrose is a “disaccharide” or “double sugar” because it contains equal parts of glucose and fructose.

  • Sources of sucrose include: white/brown sugar, turbinado sugar, maple syrup, jelly beans, gummies, and more processed candies/snacks

This means half of the carbohydrates in a packet of white sugar will raise your blood sugar quickly and the other half will be metabolized by your liver.

While fast-acting carbohydrates containing sucrose are obviously the best option if it’s the only option you have, being prepared with glucose-containing carbohydrates means raising your blood sugar sooner and faster.

The Bottom Line

Low blood sugars are a real part of living with diabetes—especially if you take insulin. Being prepared for low blood sugars comes down to having fast-acting carbohydrates in all the right places. The fastest carbohydrate—glucose tabs or glucose gel—are easy to store in your car, your purse, your nightstand, your gym bag, your desk, and your winter coat because they don’t freeze, melt or rot.

If you’re tired of waiting for the carbohydrates in a granola bar or a bag of gummies to raise your blood sugar, it might be time to take a closer look at the types of sugar in the foods you’re choosing to treat lows.

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Read more about Apple, blood glucose/sugar, hypoglycemia, insulin, Intensive management, low blood sugar (hypoglycemia).

Author: Mabel Freeman